| ncRNA name | PKR siRNA |
| ncRNA Category | siRNA |
| Disease name | choroidal neovascularization (CNV) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RPE cell line ARPE-19 |
| Methods | siRNA transfection, in vitro tube formation assay, Western blot, immunofluorescence, Fundus fluorescein angiography |
| Expression pattern | associated |
| Functional description | PKR promotes CNV formation via the PI3K/Akt signaling pathway in VEGF expression.In the ARPE-19 (RPE cell line) and RF/6A cell coculture system, PKR siRNA reduced the migration and tube formation of the RF/6A cells. |
| PubMed ID | 27994435 |
| Year | 2016 |
| Title | PKR promotes choroidal neovascularization via upregulating the PI3K/Akt signaling pathway in VEGF expression. |
| Drug-related ncRNA | NO |
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